An Endogenous Retrovirus Vaccine Encoding an Envelope with a Mutated Immunosuppressive Domain in Combination with Anti-PD1 Treatment Eradicates Established Tumours in Mice Viruses.

April 6, 2023

Daradoumis J, Ragonnaud E, Skandorff I, Nielsen KN, Bermejo AV, Andersson AM, Schroedel S, Thirion C, Neukirch L, Holst PJ

Cancer Immunology Research

Efficacy and Synergy with Cisplatin of an Adenovirus Vectored Therapeutic E1E2E6E7 Vaccine against HPV Genome-Positive C3 Cancers in Mice. Cancer Immunol Res.

February 3, 2023

International Journal of Molecular Sciences

Immunogenicity of Human Endogenous Retroviral Proteins in Cancer and Discussion of Therapeutic Approaches.

January 25, 2022

Vaccines (Basel)

Novel Antigenic Targets of HPV Therapeutic Vaccines. Vaccines (Basel)

November 1, 2021

Boilesen DR, Nielsen KN, Holst PJ.

Frontiers in Immunology

Design and Immunological Validation of Macaca fascicularis Papillomavirus Type 3 Based Vaccine Candidates in Outbred Mice: Basis for Future Testing of a Therapeutic Papillomavirus Vaccine in NHPs. Front Immunol.

October 28, 2021

Neckermann P, Boilesen DR, Willert T, Pertl C, Schrödel S, Thirion C, Asbach

Science Translational Medicine

MHC class II invariant chain-adjuvanted viral vectored vaccines enhances T cell responses in humans

June 17, 2020

Esposito I, Cicconi P, D’Alise AM, et al.

Expert Review of Vaccines

The potential of adenoviral vaccine vectors with altered antigen presentation capabilities. Expert Rev Vaccines

January 2020

Neukirch L, Fougeroux C, Andersson AC, Holst PJ.

International Journal of Molecular Sciences

Cancer Associated Endogenous Retroviruses: Ideal Immune Targets for Adenovirus-Based Immunotherapy.


Bermejo AV, Ragonnaud E, Daradoumis J, Holst PJ.


Adenovirus-Based Virus-Like-Vaccines Targeting Endogenous Retroviruses Can Eliminate Growing Colorectal Cancers in Mice.


Neukirch L, Nielsen TK, Laursen H, Daradoumis J, Thirion C, Holst PJ.


Replication Deficient Human Adenovirus Vector Serotype 19a/64: Immunogenicity in Mice and Female Cynomolgus Macaques


Ragonnaud E, Schroedel S, Mariya S, Iskandriati D, Pamungkas J, Fougeroux C, Daradoumis J, Thomsen A. R., Neukirch L, Ruzsics Z, Salomon M, Thirion C, Holst PJ.


Virus-Like-Vaccines Against HIV


Andersson A. M. C., Schwerdtfeger M., Holst P. J.


Mucosal Vaccination with Heterologous Viral Vectored Vaccine Targeting Subdominant SIV Accessory Antigens Strongly Inhibits Early Viral Replication.


Xu H., Andersson A. M., Ragonnaud E., Boilesen D., Tolver A., Jensen B. A. H., Blanchard J. L., Nicosia A., Folgori A., Colloca S., Cortese R., Thomsen A. R., Christensen J. P., Veazey R. S., Holst P. J.


Novel Adenovirus Encoded Virus-Like Particles Displaying the Placental Malaria Associated VAR2CSA Antigen.


Andersson A. M. C., Resende M., Salanti A., Nielsen M. A., Holst P. J.

Journal of Immunotherapy

Therapeutic Vaccine Against Primate Papillomavirus Infections of the Cervix.


Ragonnaud E., Andersson A. M. C., Mariya S., Pedersen A. G., Burk R. D., Folgori A., Colloca S., Cortese R., Nicosia A., Pamungkas J., Iskandriati D., Holst P. J.

Journal of Translational Medicine

Increased T Cell Breadth and Antibody Response Elicited in Prime-Boost Regimen by Viral Vector Encoded Homologous SIV Gag/Env in Outbred CD1 Mice.


Andersson A. M. C., Holst P. J.


Effect of HIV-1 Envelope Cytoplasmic Tail on Adenovirus Primed Virus-Encoded Virus-Like Particle Immunizations.


Xu H., Andersson A. M. C., Ragonnaud E., Seaton K. E., Sawant S., Folgori A., Colloca S., Labranche S., Montefiori D. C., Tomaras G. D., Holst P. J.

Molecular Cancer Research

Oncofetal Chondroitin Sulfate Glycosaminoglycans Are Key Players in Integrin Signaling and Tumor Cell Motility.

September 2016

Clausen T. M., Pereira M. A., Nakouzi N. A., Oo H. Z., Agerbæk M. Ø., Lee S., Ørum-Madsen M. S., Kristensen A. R., El-Naggerm A., Grandgenett P. M., Grem J. L., Hollingsworth M. A., Holst P. J., Theander T., Sorensen P. H., Daugaard M., Salanti A.